Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.

• Mohsin NU Faculty of Pharmaceutical Sciences, Government College University, Allama Iqbal Road, 38000 Faisalabad, Pakistan; Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstrasse 1, 8010 Graz, Austria.
• Seebacher W Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstrasse 1, 8010 Graz, Austria. Electronic address: we.seebacher@uni-graz.at.
• Faist J Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstrasse 1, 8010 Graz, Austria.
• Hochegger P Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstrasse 1, 8010 Graz, Austria.
• Kaiser M Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland; University of Basel, Petersplatz 1, 4003 Basel, Switzerland.
• Mäser P Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland; University of Basel, Petersplatz 1, 4003 Basel, Switzerland.
• Belaj F Institute of Chemistry, University of Graz, Universitätsplatz 1, 8010 Graz, Austria.
• Saf R Institute for Chemistry and Technology of Organic Materials (ICTM), Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
• Kretschmer N Institute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria.
• Alajlani M Institute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria.
• Turek I Institute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria.
• Brantner A Institute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria.
• Bauer R Institute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria.
• Bucar F Institute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria.
• Weis R Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstrasse 1, 8010 Graz, Austria.

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Anticancer

Antimicrobial

Antiprotozoal

Benzyl tetrahydropiperidinylidene ammonium salts

Animals

Anti-Bacterial Agents

Antifungal Agents

Antineoplastic Agents

Antiprotozoal Agents

Bacteria

Benzyl Compounds

Cell Line, Tumor

Cell Proliferation

Dose-Response Relationship, Drug

Drug Screening Assays, Antitumor

Humans

Mice

Microbial Sensitivity Tests

Molecular Structure

Parasitic Sensitivity Tests

Plasmodium falciparum

Pyridines

Quaternary Ammonium Compounds

Rats

Saccharomyces cerevisiae

Salts

Structure-Activity Relationship

Trypanosoma brucei rhodesiense