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Mechanisms of pathogen entry through the endosomal compartments.
Journal article

Mechanisms of pathogen entry through the endosomal compartments.

  • Gruenberg J Department of Biochemistry, University of Geneva, 30 quai Ernest Ansermet, 1211 Geneva, Switzerland. jean.gruenberg@biochem.unige.ch
  • van der Goot FG
  • 2006-06-15
Published in:
  • Nature reviews. Molecular cell biology. - 2006
Animals
Bacteria
Cell Membrane
Endocytosis
Endosomes
Infections
Intracellular Membranes
Lysosomes
Viruses
English Several pathogens - bacteria, viruses and parasites - must enter mammalian cells for survival, replication and immune-system evasion. These pathogens generally make use of existing cellular pathways that are designed for nutrient uptake, receptor downregulation and signalling. Because most of these pathways end in lysosomes, an organelle that is capable of killing microorganisms, pathogens have developed remarkable means to avoid interactions with this lytic organelle.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://susi.usi.ch/global/documents/117793
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