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Annoni_2022_PLOS_pone
Journal article

Investigating men’s motivations to engage in genetic screening for BRCA1 and BRCA2 mutations

  • Annoni, Anna Maria ORCID Institute of Public Health (IPH), Faculty of Biomedical Sciences, Università della Svizzera italiana, Switzerland - Department of Business Economics, Competence Centre on Ageing, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Manno, Switzerland
  • Longhini, Claudia Institute of Public Health (IPH), Università della Svizzera italiana, Switzerland
  • 2022
Published in:
  • PLoS ONE. - 2022, vol. 17, no. 3, p. e0265387
English BRCA1 and BRCA2 mutations are associated with an increased risk of developing numerous cancers, including breast, ovarian, pancreatic, melanoma and prostate cancer. Men face BRCA-related cancer risks as women do. However, there is considerably less research on the psychological determinants of men engaging in BRCA1/2-related cancer prevention compared to women. The present research aimed to study the determinants of men’s motivations to engage in genetic screening for BRCA1 and BRCA2 through the lens of the Health Action Process Approach. One hundred and twenty-five men (mean age = 58.53 y/o, SD = 10.37) completed an online survey. The intention to undergo genetic screening for BRCA1/2 mutations in men was significantly and positively associated with self-efficacy and risk perception. Moreover, having offspring positively affected intention as well. The relationships between intention (and planning) and positive outcome expectancies, age, and family history of breast-related cancer were not statistically significant. Most information on BRCA1 and BRCA2 mutations is tailored to women due to the availability of effective surgical risk reduction procedures for women’s breast and ovarian cancer. Future research should focus on the best methods of communicating informed decision-making for men facing the risk of such mutations.
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Language
  • English
Classification
Medicine
License
CC BY
Open access status
gold
Identifiers
  • ARK ark:/12658/srd1322460
Persistent URL
https://n2t.net/ark:/12658/srd1322460
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