Rossi, Stefania Prodi, Elena Morese, Rosalba Paone, Gaetano Ruberto, Teresa Sacco, Leonardo 2023 At least 10% of patients experience persistent symptoms after SARS-CoV-2 infection, a condition referred to as post-acute COVID-19, post-acute sequelae of SARS-CoV-2 infection (PASC), long COVID, long-haul COVID, long-term effects of COVID, post-COVID-19 and chronic COVID. In this report, we describe a case of persistent cognitive deficits developed after SARS-CoV-2 infection in a 40-year-old woman with a family history of early-onset Alzheimer’s disease (EOAD) since her father was diagnosed with EOAD at the age of 50. We describe the clinical picture and workup, with special emphasis on the alterations of brain glucose metabolism evidenced by 18-fluoro-deoxy-glucose positron emission tomography (FDG-PET), which could be considered a useful marker of the presence and persistence of cognitive deficits. application/pdf https://susi.usi.ch/global/documents/332023 https://n2t.net/ark:/12658/srd1332023 https://susi.usi.ch/documents/332023/files/Morese_2023_MDPI_Neurolint_Persistent 18F-FDG Brain.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.3390/neurolint15030058 info:eu-repo/semantics/altIdentifier/ark/12658/srd1332023 info:eu-repo/semantics/openAccess CC BY Neurology International. - 2023, vol. 15, no. 3, p. 908–916 SARS-CoV-2 Post-COVID-19 Cognitive impairment Alzheimer’s disease FDG-PET info:eu-repo/classification/udc/61 Persistent 18F-FDG brain PET fronto-temporal hypometabolism and cognitive symptoms two years after SARS-CoV-2 infection : a case report http://purl.org/coar/resource_type/c_6501