<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Trimboli, Pierpaolo</dc:creator>
  <dc:creator>Camponovo, Chiara</dc:creator>
  <dc:creator>Scappaticcio, Lorenzo</dc:creator>
  <dc:creator>Bellastella, Giuseppe</dc:creator>
  <dc:creator>Piccardo, Arnoldo</dc:creator>
  <dc:creator>Rotondi, Mario</dc:creator>
  <dc:date>2021-04-11</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to cause multi- organ effects including endocrine disorders. The impact of COVID-19 on the thyroid gland has been described but several aspects have to be clarified. The  systematic review was conceived to achieve more solid information about: 1) which thyroid disease or dysfunction should be expected in COVID-19 patients;  2) whether thyroid patients have a higher risk of SARS-CoV-2 infection; 3) whether the management has to be adapted in thyroid patient when infected. The  literature was searched by two authors independently. A 5-step search strategy was a priori adopted. Only reviews focused on the relationship between  thyroid and COVID-19 were included. The last search was performed on February 21st 2021. Two-hundred-forty-seven records was initially found and nine  reviews were finally included. The reviews identified several potential thyroid consequences in COVID-19 patients, such as thyrotoxicosis, low-T3 syndrome  and subacute thyroiditis, while no relevant data were found regarding the potential impact of COVID-19 on the management of patients on thyroid treatment.  The present systematic review of reviews found that: 1) patients diagnosed with COVID-19 can develop thyroid dysfunction, frequently non-thyroidal illness  syndrome when hospitalized in intensive care unit, 2) having a thyroid disease does not increase the risk for SARS-CoV-2 infection, 3) thyroid patients do not  need a COVID-19-adapted follow-up. Anyway, several factors, such as critical illness and medications, could affect thyroid laboratory tests.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://n2t.net/ark:/12658/srd1319348</dc:identifier>
  <dc:identifier>https://susi.usi.ch/global/documents/319348</dc:identifier>
  <dc:identifier>https://susi.usi.ch/documents/319348/files/Trimboli_remd_2021.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1007/s11154-021-09653-1</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/ark/12658/srd1319348</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>CC BY</dc:rights>
  <dc:source>Reviews in Endocrine and Metabolic Disorders. - Springer. - 2021, vol. 22, no. 2, p. 485-491</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Thyroid</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">COVID-19</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Coronavirus</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Thyroiditis</dc:subject>
  <dc:subject>info:eu-repo/classification/udc/61</dc:subject>
  <dc:title xmlns:ns5="xml" ns5:lang="en">Thyroid sequelae of COVID-19 : a systematic review of reviews</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>