Oluwaseyi Temilola, Dada Wium, Martha Coulidiati, Tangbadioa Herve Adeola, Henry Ademola Carbone, Giuseppina Maria Catapano, Carlo Vittorio Zerbini, Luiz Fernando 2019-08-09 Liquid biopsy technologies have the potential to transform cancer patient management as it others non- invasive diagnosis and real-time monitoring of disease progression and treatment responses. The use of liquid biopsy for non-invasive cancer diagnosis can have pivotal importance for the African continent where access to medical infrastructures is limited, as it eliminates the need for surgical biopsies. To apply liquid biopsy technologies in the African setting, the influence of environmental and population genetic factors must be known. In this review, we discuss the use of circulating tumor cells, cell-free nucleic acids, extracellular vesicles, protein, and other biomolecules in liquid biopsy technology for cancer management with special focus on African studies. We discussed the prospect, barriers, and other aspects that pose challenges to the use of liquid biopsy in the African continent. application/pdf https://n2t.net/ark:/12658/srd1319062 https://susi.usi.ch/global/documents/319062 https://susi.usi.ch/documents/319062/files/Oluwaseyi_Temilola_C_2019.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.3390/cells8080862 info:eu-repo/semantics/altIdentifier/ark/12658/srd1319062 info:eu-repo/semantics/openAccess CC BY Cells. - 2019, vol. 8, no. 8, p. 862 Africa Cancer Cell-free DNA Circulating tumor cell Circulating RNA Liquid biopsy Non-invasive info:eu-repo/classification/udc/61 The prospect and challenges to the flow of liquid biopsy in Africa http://purl.org/coar/resource_type/c_6501