Rusca, Nicole Monticelli, Silvia 2011-02-17 MicroRNAs (miRNAs) are regulatory molecules able to influence all aspects of the biology of a cell. They have been associated with diseases such as cancer, viral infections, and autoimmune diseases, and in recent years, they also emerged as important regulators of immune responses. MiR-146a in particular is rapidly gaining importance as a modulator of differentiation and function of cells of the innate as well as adaptive immunity. Given its importance in regulating key cellular functions, it is not surprising that miR-146a expression was also found dysregulated in different types of tumors. In this paper, we summarize recent progress in understanding the role of miR- 146a in innate and adaptive immune responses, as well as in disease. application/pdf https://localhost:5000/ark:/12658/srd1319048 https://susi.usi.ch/global/documents/319048 https://susi.usi.ch/documents/319048/files/rusca_mbi_2011.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.4061/2011/437301 info:eu-repo/semantics/altIdentifier/ark/12658/srd1319048 info:eu-repo/semantics/openAccess CC BY Molecular biology international. - 2011, vol. 2011, p. 1-7 info:eu-repo/classification/udc/61 MiR-146a in immunity and disease http://purl.org/coar/resource_type/c_6501