Garofalo, Mariangela Grazioso, Giovanni Cavalli, Andrea Sgrignani, Jacopo 2020-04-10 The early and late development of new anticancer drugs, small molecules or peptides can be slowed down by some issues such as poor selectivity for the target or poor ADME properties. Computer-aided drug design (CADD) and target drug delivery (TDD) techniques, although apparently far from each other, are two research fields that can give a significant contribution to overcome these problems. Their combination may provide mechanistic understanding resulting in a synergy that makes possible the rational design of novel anticancer based therapies. Herein, we aim to discuss selected applications, some also from our research experience, in the fields of anticancer small organic drugs and peptides. application/pdf https://susi.usi.ch/global/documents/319015 https://n2t.net/ark:/12658/srd1319015 https://susi.usi.ch/documents/319015/files/Cavalli_molecules_2020.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules25071756 info:eu-repo/semantics/altIdentifier/ark/12658/srd1319015 info:eu-repo/semantics/openAccess CC BY Molecules. - 2020, vol. 25, no. 7, p. 22 p Drug delivery Computational chemistry Anticancer drug design info:eu-repo/classification/udc/615 How computational chemistry and drug delivery techniques can support the development of new anticancer drugs http://purl.org/coar/resource_type/c_6501